Contrast-Enhanced Spectral Mammography

Routine mammograms play an important role in detecting breast cancer. For many women, standard imaging provides the clarity needed. But in some cases, a more detailed look helps uncover what may not be visible on standard exams.

Contrast-enhanced spectral mammography (CESM) offers a more complete view of breast tissue and breast health. By using contrast dye, CESM helps reduce uncertainty and provide a stronger foundation for diagnosis and treatment planning.

What Is Contrast-Enhanced Spectral Mammography?

CESM combines traditional mammography with a contrast agent to provide a clearer view of breast tissue. The contrast material is administered through an intravenous (IV) line before imaging, allowing radiologists to identify areas of increased blood flow that may be associated with cancer.

This type of imaging is used to provide additional detail when standard imaging results are unclear or when more information is needed to guide care.

Benefits of Using CESM

Contrast-enhanced spectral mammography offers additional insight and key benefits, including:

  • Detection of cancers not visible on standard mammography
  • Visualization of increased blood flow in abnormal tissue
  • Greater clarity in dense breast tissue
  • Detailed evaluation of abnormal findings or symptoms
  • An alternative to MRI for certain patients
  • Faster imaging results to support timely decisions

Who May Benefit from CESM

When more detailed imaging is needed to better understand a breast concern, contrast-enhanced spectral mammography may be recommended for patients with:

  • Dense breast tissue
  • Abnormal findings on a screening mammogram
  • Breast symptoms (e.g., lump, nipple discharge or skin changes)
  • Increased risk for breast cancer
  • A need for further evaluation of a breast concern
  • An inability to undergo breast MRI due to allergies, claustrophobia or implanted devices

While contrast-enhanced spectral mammography is approved as a diagnostic tool, its use for routine screening varies. Individual recommendations depend on clinical history and provider guidance. A physician order and radiologist recommendation are required.

What to Expect During the Exam

Contrast-enhanced spectral mammography is similar to a standard mammogram, with an added step for contrast administration.

  • An intravenous (IV) contrast agent is administered before imaging
  • The imaging process is performed using mammography equipment
  • The exam typically includes multiple images to capture detailed views
  • The entire appointment is generally brief

Advanced Breast Imaging and Support Services

Contrast-enhanced spectral mammography is part of a broader approach to breast health that may include additional imaging and follow-up care, including:

  • 3D mammography
  • Breast ultrasound
  • Biopsy services

A Focus on Early Detection and Clarity

Early detection plays an important role in improving breast cancer outcomes. Advanced imaging tools, like contrast-enhanced spectral mammography, help provide clearer answers, supporting more timely and informed care.

Schedule an Appointment

To schedule a breast imaging appointment or learn more about available services, contact the radiology department at 931.538.1557.


Talk with your provider about your family history, areas of concern, and breast cancer risk. The sooner any form of breast cancer is detected, the greater the likelihood that treatment will be successful.

Schedule your screening mammogram today by calling 931.538.1557.

Find A Provider

Some breast screenings may require a provider order. Talk to your provider or find one today.